Medical Research Continues to Lose Integrity

Senator Charles E. Grassley has raised some serious concern over a recent article published in the Elsevier Medical Journal. The Senator has asked the publisher to investigate an article written on hormone replacement therapy, believing that it was improperly “ghostwritten” by a drug company promoting their products. The article was part of an editor’s choice section in Elsevier’s Journal of Obstetrics and Gynecology.

In an article signed by Dr. John Eden of Australia, Senator Grassley has found unethical promotions lacking scientific evidence. At the heart of the controversy is the drug company Wyeth. Mr. Grassley, a member of the Senate Finance Committee who is investigating drug company influence on doctors, contends that Wyeth commissioned the articles and had them ghostwritten by a medical writing firm. Only after the articles were conceived and under way did the firm line up doctors to put their names on them, Mr. Grassley contends.

Unfortunately, this is not an isolated incident. Drug companies have been forcing their will on medical research results for decades now, and the influence of corporate profit is on the rise. By 2006, Drug companies were spending nearly twice as much on advertising and marketing as they were on the research and testing needed to ensure the safety of a new product.

Mr. Grassley’s investigation shows how results of this corporate policy can be catastrophic. A landmark federal study has linked Wyeth’s Prempro hormone product to breast cancer in women. What does the expert testimony sponsored by Wyeth say about that taxpayer funded study? Dr. Eden’s controversial article states that, “there was no definitive evidence that the [Wyeth] hormones caused breast cancer.”

It seems the Wyeth Corporation and Dr. Eden have forgotten the meaning of the Hippocratic oath.

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Morphine, Dextroamphetamine, and Isosorbide added to the Ethex Recall

The Ethex Corporation has added three new drugs to its list of recently recalled products.  After Ethex discovered that their propafenone tablets were over-sized, it became evident that many other drugs being manufactured by the company were also over-sized. 

Isosorbide

Isosorbide is a drug used principally in the treatment of angina. It works by dilating the blood vessels in order to reduce blood pressure. All of the recalled Isosorbide Mononitrate tablets said they were 60mg on the bottle and were made by the ETHEX Corporation with expiration dates ranging from 12/2008 and 11/2009.

Recalled lot numbers: 63466, 66034, 67351, and 67354

Dextroamphetamine

Dextroamphetamine is a stimulant used to increase energy and decrease appetite.  The recalled Dextroamphetamine Sulfate came in 10mg pills with expiration dates ranging from 6/2009 to 5/2007. All were made by the ETHEX Corporation.

Recalled lot numbers: 73934, 75892, 77945, 81137, 86320.

Amphetamines are very dangerous drugs, especially when taken in excessive doses. If the batch number on your pill bottle matches any of the above recalled Dextroamphetamine batch numbers you should contact your doctor and/or pharmacists immediately.

Morphine

Two strengths of immediate release Morphine Sulfate and one strength of extended release Morphine Sulfate were recalled, all of them tablets made by the ETHEX Corporation. The two recalled Morphine immediate release pills were 15mg and 30mg. The recalled Morphine extended release pills were 15mg.  The recalled tablets come from any of the following lots with expiration dates ranging from 8/2009 to 3/2011.

Recalled Lot Numbers:

15mg Extended Release Morphine – 81175, 82514-16, 89660, 89664, 89667, 90249-51, 91687
15mg Immediate Release Morphine – 77852-54, 81746, 82519-20, 84113, 90276-78
30mg Immediate Release Morphine – 75093, 77855-57, 82297, 82521-22, 87239, 88925, 90288-98

Morphine is a highly potent and addictive drug in the opiate family. Like other opioids, such as heroin, morphine acts on the central nervous system to relieve pain. Morphine is highly addictive. Tolerance, physical and psychological dependence develops very rapidly. Overdosing on Morphine is very dangerous and can result in severe side effects, including death.

 If you or anyone you know is prescribed any of these drugs, please immediately check the manufacturer and lot number on your pill bottle.  Contact your physician immediately.  Even in the case that you don’t think you have a recalled prescription; call your pharmacy and physician to confirm. 

 If you or a family member has been hurt by any of the Ethex Corporation recalled drugs, please contact an attorney immediately.  You may be entitled to compensation. 

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